ALT Telomeres Borrow from Meiosis to Get Moving

نویسندگان

  • Nausica Arnoult
  • Jan Karlseder
چکیده

Telomere clustering is required for the homologous recombination events that maintain chromosome ends in cells relying on alternative lengthening of telomeres (ALT). New data demonstrate that damage signaling at telomeres, a likely step in activating maintenance mechanisms, induces directional movement and synapsis driven by the machinery responsible for recombination in meiosis.

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عنوان ژورنال:
  • Cell

دوره 159  شماره 

صفحات  -

تاریخ انتشار 2014